DL-Thioctic acid

Specifications & Purity: 99%

For research use only. We do not sell to patients.

CAS#: 1077-28-7
Formula: C₈H₁₄O₂S₂
Molecular Weight : 206.33
Beilstein Registry Number: 81853
EC Number: 214-071-2
MDL number: MFCD00005474
PubChem CID: 864

Item Number

T106640

Grouped product items
SKU	Size	Availability	Price
T106640-5g	5g	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	$205.90
T106640-25g	25g	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	$594.90
T106640-100g	100g	Available within 1-2 weeks(?) Item is derived from our semi-finished stock and is processed in 1-2 weeks.	$1,647.90
T106640-500g	500g	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$6,591.90

Non-specific free radical scavenger. Anti-oxidant.

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Basic Description

Synonyms	DL-α-Lipoic Acid; DL-Thioctic Acid; 1,2-Dithiolane-3-valeric acid; DL-6,8-Dithiooctanoic acid; (±)-α-Lipoic acid; Lip(S2)
Specifications & Purity	99%
Storage Temp	Store at 2-8°C,Argon charged
Shipped In	Wet ice
Description	α-Lipoic acid (LA), a nutritional component found in vegetables and meat, has both antioxidant and oxidant properties. LA exerts therapeutic potential to many diseases like liver cirrhosis, heavy metal poisoning, and diabetic polyneuropathy. LA exerts apoptotic potential in cancer cells either by oxidative stress related pathway or by activation of caspases. DL-Thioctic acid acid has been used in in vitro lipoylation studies and in the pyruvate dehydrogenase complex (PDC)-pyruvate dehydrogenase kinase (PDHK) functional assay.It has also been used to investigate its antioxidative effect on developing cerebellum of rats exposed to arsenic during postnatal period; DL-Thioctic acid can reinstate endothelial activities and alleviate oxidative stress in high-fat fed diabetic rats. It has also been used to analyze ROS production in astrocytes

Names and Identifiers

IUPAC Name	5-(dithiolan-3-yl)pentanoic acid
INCHI	InChI=1S/C8H14O2S2/c9-8(10)4-2-1-3-7-5-6-11-12-7/h7H,1-6H2,(H,9,10)
InChi Key	AGBQKNBQESQNJD-UHFFFAOYSA-N
Canonical SMILES	C1CSSC1CCCCC(=O)O
WGK Germany	3
RTECS	JP1192000
PubChem CID	864
Molecular Weight	206.33
Beilstein	81853
Reaxy-Rn	81851

Certificates

Certificate of Analysis(COA)

Enter Lot Number to search for COA:

To view the certificate results,please click on a Lot number.For Lot numbers from past orders,please use our order status section

17 results found

Lot Number	Certificate Type	Date	Item
I2314293	Certificate of Analysis	Aug 16, 2023	T106640
I2314292	Certificate of Analysis	Aug 16, 2023	T106640
B23111172	Certificate of Analysis	Jan 09, 2023	T106640
B23111180	Certificate of Analysis	Jan 09, 2023	T106640
B23111179	Certificate of Analysis	Jan 09, 2023	T106640
B23111171	Certificate of Analysis	Jan 09, 2023	T106640
B23111127	Certificate of Analysis	Jan 09, 2023	T106640
B23111124	Certificate of Analysis	Jan 09, 2023	T106640
B23111114	Certificate of Analysis	Jan 09, 2023	T106640
G2230399	Certificate of Analysis	Jul 12, 2022	T106640
G2230421	Certificate of Analysis	Jul 12, 2022	T106640
G2230438	Certificate of Analysis	Jul 12, 2022	T106640
G2230451	Certificate of Analysis	Jul 12, 2022	T106640
B2225735	Certificate of Analysis	Dec 18, 2021	T106640
B2226184	Certificate of Analysis	Dec 18, 2021	T106640
B2225762	Certificate of Analysis	Dec 18, 2021	T106640
B2225741	Certificate of Analysis	Dec 18, 2021	T106640

Chemical and Physical Properties

Solubility	Soluble in methanol, ethanol, diethyl ether and chloroform. Insoluble in water.
Sensitivity	Air & Moisture & Heat & Light Sensitive
Boil Point(°C)	160-165℃
Melt Point(°C)	62°C

Safety and Hazards(GHS)

Pictogram(s)	GHS09,GHS07
Signal	Warning
Hazard Statements	H315,H319,H411,H302,H317
Precautionary Statements	P261,P305+P351+P338,P273,P280,P302+P352,P321,P501,P264,P270,P272,P333+P313,P362+P364,P391,P330,P264+P265,P301+P317,P337+P317,P332+P317
WGK Germany	3
RTECS	JP1192000
Reaxy-Rn	81851
Merck Index	9326

Pictogram(s)

GHS09,GHS07

Signal

Warning

Hazard Statements

H315,H319,H411,H302,H317

Precautionary Statements

P261,P305+P351+P338,P273,P280,P302+P352,P321,P501,P264,P270,P272,P333+P313,P362+P364,P391,P330,P264+P265,P301+P317,P337+P317,P332+P317

WGK Germany

RTECS

JP1192000

Reaxy-Rn

81851

Merck Index

9326

CTH Tchem Cystathionine gamma-lyase 7 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

C7orf77 Tdark Uncharacterized protein C7orf77 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

C8orf34 Tbio Uncharacterized protein C8orf34 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CGGBP1 Tbio CGG triplet repeat-binding protein 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

C8orf76 Tdark Uncharacterized protein C8orf76 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHD1 Tbio Chromodomain-helicase-DNA-binding protein 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHERP Tbio Calcium homeostasis endoplasmic reticulum protein 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHP1 Tbio Calcineurin B homologous protein 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CAMTA2 Tbio Calmodulin-binding transcription activator 2 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNBD1 Tdark Cyclic nucleotide-binding domain-containing protein 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNBD2 Tdark Cyclic nucleotide-binding domain-containing protein 2 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

COMTD1 Tdark Catechol O-methyltransferase domain-containing protein 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

NCAPD3 Tbio Condensin-2 complex subunit D3 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CMTR2 Tbio Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CTNNBIP1 Tbio Beta-catenin-interacting protein 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNDP2 Tbio Cytosolic non-specific dipeptidase 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

PDE6H Tclin Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CTDNEP1 Tbio CTD nuclear envelope phosphatase 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNFN Tdark Cornifelin 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CNKSR1 Tchem Connector enhancer of kinase suppressor of ras 1 30 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)