Tetramethylrhodamine hyaluronic acid from Streptococcus equi

Specifications & Purity: average mol wt 5000000

For research use only. We do not sell to patients.

Item Number

T292214

Grouped product items
SKU	Size	Availability	Price
T292214-25mg	25mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$446.90
T292214-100mg	100mg	Available within 4-8 weeks(?) Items will be manufactured post-order and can take 4-8 weeks. Thank you for your patience!	$1,235.90

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Basic Description

Synonyms	T-hyaluronic acid;Tetramethylrhodamine Hyaluronic Acid;Tetramethyl-rhodamine hyaluronic acid Hyaluronan；Tetramethyl-rhodamine B hyaluronan;6´bis(tetramethylamino) -3-oxospiro(isobenzofuran-1(3H),9´-9H]xanthen]-5(or 6)- yl).
Specifications & Purity	average mol wt 5000000
Storage Temp	Store at -20°C,Argon charged,Desiccated
Shipped In	Dry ice
Description	THA-Se is supplied a red solid which is soluble in water. Tetramethyl-rhodamine hyaluronic acid (THA-Se) has similar applications to those described for fluorescein hyaluronic acid (see FHA-Se) but has certain advantages. As mentioned earlier, the fluorescence of tetramethyl-rhodamine is less dependent on pH than FITClabels. Also, the longer emission wavelength avoids interference from background images in experimental environments. Invasive growth into brain tissue employing TR-HA and 2-photon imaging has been described. Hyaluronic acid (HA) can be obtained from various sources, for example rooster combs or Streptococcus equi. We can supply derivatives of either of these qualities labelled with or with tetramethylrhodamine (T-Ha). All batches are checked for molecular weight, degree of substitution, loss on drying and free TRITC. Hyaluronic acid is a polysaccharide composed of alternating β(1-3) glucuronide and β(1-4) glucosaminide units derived from Streptococcus equi. The hyaluronic acid is labelled with amino-tetramethylrhodamine. The degree of substitution lies between 0.001 and 0.008. The labelling procedures do not lead to depolymerisation of the HA. Spectral data T-Ha has an excitation maximum at 552 nm and an emission maximum at 576 nm. Application T-Ha have been used to e.g. investigate invasive growth into brain tissue.

Certificates

Certificate of Analysis(COA)

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2 results found

Lot Number	Certificate Type	Date	Item
A2211640	Certificate of Analysis	Dec 22, 2021	T292214
A2211755	Certificate of Analysis	Dec 22, 2021	T292214

Chemical and Physical Properties

Solubility	dissolves readily in water
Sensitivity	air sensitive

CTH Tchem Cystathionine gamma-lyase 7 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

C7orf77 Tdark Uncharacterized protein C7orf77 0 Activities

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C8orf34 Tbio Uncharacterized protein C8orf34 0 Activities

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CGGBP1 Tbio CGG triplet repeat-binding protein 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

C8orf76 Tdark Uncharacterized protein C8orf76 0 Activities

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CHD1 Tbio Chromodomain-helicase-DNA-binding protein 1 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CHERP Tbio Calcium homeostasis endoplasmic reticulum protein 0 Activities

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CHP1 Tbio Calcineurin B homologous protein 1 0 Activities

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CAMTA2 Tbio Calmodulin-binding transcription activator 2 0 Activities

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CNBD1 Tdark Cyclic nucleotide-binding domain-containing protein 1 0 Activities

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CNBD2 Tdark Cyclic nucleotide-binding domain-containing protein 2 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

COMTD1 Tdark Catechol O-methyltransferase domain-containing protein 1 0 Activities

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NCAPD3 Tbio Condensin-2 complex subunit D3 0 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)

CMTR2 Tbio Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 2 0 Activities

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CTNNBIP1 Tbio Beta-catenin-interacting protein 1 0 Activities

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CNDP2 Tbio Cytosolic non-specific dipeptidase 0 Activities

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PDE6H Tclin Retinal cone rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit gamma 0 Activities

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CTDNEP1 Tbio CTD nuclear envelope phosphatase 1 0 Activities

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CNFN Tdark Cornifelin 0 Activities

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CNKSR1 Tchem Connector enhancer of kinase suppressor of ras 1 30 Activities

Activity Type	Activity Value -log(M)	Mechanism of Action	Activity Reference	Publications (PubMed IDs)